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KMID : 0644120230360010035
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Journal of Oriental Gynecology
2023 Volume.36 No. 1 p.35 ~ p.53
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Research Trends of Animal Experiment on the Herbal Medicine Treatment for Endometriosis
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Lee Ji-Young
Hwang Deok-Sang
Lee Jin-Moo
Lee Chang-Hoon
Jang Jun-Bock
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Abstract
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Objectives: The aim of this study is to investigate the research trends of animal experiment on the herbal medicine treatment for endometriosis over the past 10 years.
Methods: We searched the databases (Pubmed, Embase, Science-on) with terms as endometriosis, Korean medicine, herbal medicine and Chinese medicine. Among the results, we reviewed studies published from 2013 to 2022.
Results: 26 studies were selected and analyzed. 8 single herbs and 18 complex formula were used in these studies. The most commonly used herbal medicine for endometriosis was Paeoniae Radix. Each studies showed that herbal medicine had significant effect on treating endometriosis.
Conclusions: These results suggest that treating endometriosis with herbal material is effective in inhibiting ectopic lesion and angiogenesis, increasing pain threshold and apoptosis. Further research should be conducted to verify its therapeutic mechanisms and effectiveness.
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KEYWORD
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Endometriosis, Herbal Medicine, Animal Experimen, , Research Trend
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